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Can a common ectopic pregnancy drug work in women with kidney or liver issues?

NCT ID NCT07186127

Knowledge-focused Sponsor: Bagcilar Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study reviews medical records of 230 women treated with methotrexate for ectopic pregnancy, focusing on those with conditions that usually make this drug risky, like kidney or liver problems. Researchers will check how well the treatment worked by measuring pregnancy hormone levels and whether surgery was needed. The goal is to gather real-world data to help doctors make better decisions for similar patients in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Methotrexate
What this could lead to
If successful, this study could help doctors understand when it is safe to use methotrexate for ectopic pregnancy in women with kidney or liver issues.
What could go wrong
This is a retrospective study, meaning it looks back at old records, not a controlled trial. Results may not apply to all patients, and the study cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 230 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients diagnosed with ectopic pregnancy and treated with methotrexate

Ages

18 to 48 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with ectopic pregnancy * Received methotrexate (MTX) treatment * Underwent surgical treatment due to lack of response to MTX therapy * Compliant with treatment follow-up Exclusion Criteria: * Participants with contraindications to methotrexate (MTX) treatment * Participants non-compliant with follow-up

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Conditions

The condition(s) this trial relates to.

ectopic pregnancy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ectopic pregnancy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Health Sciences, Training and Research Hospital

    RECRUITING

    Istanbul, Türkiye, 34200, Turkey (Türkiye)

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