Can a drug combo calm the immune system in spine arthritis?
NCT ID NCT01895764
First seen Jan 04, 2026 · Last updated May 01, 2026 · Updated 16 times
Summary
This study looked at whether adding methotrexate to adalimumab (a biologic) lowers the chance of the body making antibodies against adalimumab in people with ankylosing spondylitis, a type of arthritis affecting the spine. About 110 adults with active disease who did not respond well to NSAIDs took part. The goal was to see if the combination keeps the treatment working longer by reducing immune reactions.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Médecine polyvalente, CH de SAINT NAZAIRE
Saint-Nazaire, 44606, France
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Rhumatologie / IPROS, CHR d'ORLEANS
Orléans, 45032, France
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Rhumatologie, CH de BLOIS
Blois, 41000, France
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Rhumatologie, CH de SAINT BRIEUC
Saint-Brieuc, 22027, France
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Rhumatologie, CHD LA ROCHE SUR YON
La Roche-sur-Yon, 85925, France
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Rhumatologie, CHR du MANS
Le Mans, 72037, France
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Rhumatologie, CHRU de BREST
Brest, 29609, France
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Rhumatologie, CHRU de NANTES
Nantes, 44093, France
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Rhumatologie, CHRU de POITIERS
Poitiers, 86021, France
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Rhumatologie, CHRU de RENNES
Rennes, 35203, France
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Rhumatologie, CHRU de TOURS
Tours, 37044, France
Conditions
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