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Could a painkiller help fight advanced colon cancer?

NCT ID NCT05212012

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 27 times

Summary

This study tests whether adding D,L-methadone (a pain medication) to standard chemotherapy (mFOLFOX6) can help control advanced colorectal cancer that has stopped responding to other treatments. The trial involves 11 participants and aims to find the safest dose and measure how well the combination shrinks or stabilizes tumors. It is not a cure, but a way to potentially manage the disease longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Stauferklinikum Schwäbisch Gmünd

    Mutlangen, 73557, Germany

  • Universitätsklinikum Hamburg Eppendorf - II. Med.

    Hamburg, 20246, Germany

  • Universitätsklinikum Ulm - Innere Med. I

    Ulm, 89081, Germany

Conditions

Explore the condition pages connected to this study.