Could a painkiller boost chemo for tough colorectal cancers?
NCT ID NCT05212012
First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 38 times
Summary
This early-stage trial tests whether adding D,L-methadone (a pain medication) to standard chemotherapy (mFOLFOX6) can help control advanced colorectal cancer that has stopped responding to other treatments. The study involves 11 participants and aims to find the safest dose and measure how well the combination works at stopping tumor growth for at least 12 weeks. It is not a cure, but a way to potentially improve disease control in a difficult-to-treat cancer.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Stauferklinikum Schwäbisch Gmünd
Mutlangen, 73557, Germany
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Universitätsklinikum Hamburg Eppendorf - II. Med.
Hamburg, 20246, Germany
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Universitätsklinikum Ulm - Innere Med. I
Ulm, 89081, Germany
Conditions
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