Could a common diabetes drug help fight TB in HIV patients?
NCT ID NCT04930744
First seen Jan 07, 2026 · Last updated May 20, 2026 · Updated 23 times
Summary
This study looked at whether adding metformin, a diabetes medicine, to the usual antibiotics for tuberculosis (TB) is safe and tolerable for people also living with HIV. 112 adults took part, and half received standard TB drugs alone while the other half also took metformin for 11 weeks. Researchers monitored side effects and checked if the infection cleared faster and caused less lung damage.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Isango Lethemba TB Research Unit
Port Elizabeth, South Africa
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Tembisa Clinical Research Centre-The Aurum Institute
Johannesburg, Gauteng, 1632, South Africa
Conditions
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