Could a common diabetes drug help delay preterm birth in preeclampsia?
NCT ID NCT06033131
First seen Apr 09, 2026 · Last updated Jun 21, 2026 · Updated 9 times
Summary
This phase 3 trial tests whether metformin, a diabetes drug, can safely prolong pregnancy in women with preterm preeclampsia. Currently, the only treatment is early delivery, which risks the baby's health. The study will enroll 294 women across Nordic countries, giving them metformin or a placebo from diagnosis until delivery. The goal is to see if metformin can extend gestation, increase birth weight, and reduce time babies need in neonatal care.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Akershus University Hospital
NOT_YET_RECRUITINGLørenskog, N-1474, Norway
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Contact
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Danderyd Hospital
RECRUITINGStockholm, 182 88, Sweden
Contact Email: •••••@•••••
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Falu Lasarett
RECRUITINGFalun, 79129, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Helsinki University Hospital
NOT_YET_RECRUITINGHelsinki, 00290, Finland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Karolinska University Hospital Huddinge
RECRUITINGStockholm, 14157, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Karolinska University Hospital Solna
RECRUITINGStockholm, 17176, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Linköping University Hospital
RECRUITINGLinköping, 581 85, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Norra Älvsborgs County Hospital
RECRUITINGTrollhättan, 461 74, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Norrland´s University Hospital
RECRUITINGUmeå, 901 85, Sweden
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Oslo University Hospital
RECRUITINGOslo, 0372, Norway
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sahlgrenska University Hospital
RECRUITINGGothenburg, 416 85, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Skåne University Hospital
RECRUITINGLund, 221 85, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Skåne University Hospital
RECRUITINGMalmö, 205 02, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Södra Älvsborgs Hospital
RECRUITINGBorås, 50455, Sweden
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tampere University Hospital
RECRUITINGTampere, 33520, Finland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Uppsala University Hospital
RECRUITINGUppsala, 75237, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Västmanlands Hospital Västerås
NOT_YET_RECRUITINGVästerås, 72335, Sweden
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Metformin (a diabetes drug)
What this could lead to
If it works, this could offer a way to safely prolong pregnancy in preterm preeclampsia, reducing complications from early delivery.
What could go wrong
This is still a trial, and metformin may not effectively delay delivery. Side effects like nausea or diarrhea are possible, and results may not apply to all populations.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.