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Diabetes drug metformin shows promise in stopping oral cancer before it starts

NCT ID NCT02581137

First seen Mar 09, 2026 · Last updated May 23, 2026 · Updated 11 times

Summary

This study tests whether metformin, a drug used for diabetes, can prevent oral cancer in people with precancerous mouth lesions like leukoplakia or erythroplakia. About 26 participants took metformin to see if it could shrink or eliminate these lesions. The goal is to stop cancer from forming in the first place.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • BC Cancer Research Centre

    Vancouver, British Columbia, V5Z 1L3, Canada

  • UC San Diego Medical Center - Hillcrest

    San Diego, California, 92103, United States

  • University of British Columbia Hospital

    Vancouver, British Columbia, V6T 2B5, Canada

  • University of Minnesota/Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.