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Common diabetes drug tested for heart failure relief in seniors

NCT ID NCT05093959

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 27 times

Summary

This study tested whether metformin, a common diabetes medicine, can improve exercise ability and quality of life in older adults with a type of heart failure called HFpEF. 86 participants took either metformin or a placebo for 20 weeks. Researchers measured changes in oxygen use during exercise, gut health, and inflammation.

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Contacts and locations

Locations

  • Atrium Health Sanger Heart and Vascular Clinic Institute

    Charlotte, North Carolina, 28203, United States

  • Wake Forest School of Medicine

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.