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Experimental enzyme therapy tested in rare child brain disease after transplant

NCT ID NCT01303146

First seen Apr 01, 2026 · Last updated May 22, 2026 · Updated 8 times

Summary

This study tested an experimental enzyme therapy called METAZYM in one child with late infantile metachromatic leukodystrophy (MLD) who had already received a stem cell transplant. The goal was to see if the enzyme could improve nerve function and reduce harmful substance buildup. The child was monitored for safety and effects on movement and thinking over time.

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Contacts and locations

Locations

  • Department of Pediatric Endocrinology and Neurology, Saint Vincent de Paul Hospital

    Paris, 75014, France

Conditions

Explore the condition pages connected to this study.