Can a Brain-Training class ease mental illness symptoms?
NCT ID NCT07051746
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a group therapy program called Metacognitive Training (MCT) in 18 Taiwanese adults with schizophrenia, major depression, or bipolar disorder. Over 4 weeks, participants attended 8 sessions that taught them to spot and reduce thinking biases linked to symptoms like delusions and low mood. The goal was to see if the program could improve symptoms, thinking skills, and daily function. Because the study was small and had no comparison group, the results are preliminary.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Metacognitive Training (MCT) – a group therapy program that teaches people to recognize and reduce thinking biases
- What this could lead to
- If it works, this could offer a low-cost, drug-free way to help people with mental disorders manage symptoms like delusions, depression, and anxiety.
- What could go wrong
- This is a very small, single-group study with no comparison group, so results may be due to chance or other factors. It also only includes people from one hospital in Taiwan, so findings may not apply to others.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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18 people
The number who actually took part.
- Started
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Oct 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 75 years. * Diagnosed with schizophrenia, major depressive disorder, or bipolar disorder based on DSM-5 criteria by a psychiatrist. * Currently enrolled in a psychiatric day hospital. * Judged by an occupational therapist as capable of understanding written/spoken Mandarin and completing Chinese-language questionnaires. * No changes in psychiatric medication within the past month. Exclusion Criteria: * History of severe hearing or visual impairments. * Severe psychiatric symptoms or attention deficits that would prevent full participation in a 60-minute session, as judged by the therapist. * Presence of inappropriate social behaviors such as aggression, sexual harassment, or antisocial behavior. * Ongoing major life crises or recent traumatic events.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Taiwan University Hospital, Department of Psychiatry, General Psychiatry Day Hospital
Taipei, Taiwan Province, 100, Taiwan
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