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Can rethinking thoughts beat standard OCD therapy?
NCT ID NCT02867449
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This trial compares two psychological treatments for obsessive-compulsive disorder (OCD): metacognitive therapy, which focuses on changing unhelpful thinking patterns, and exposure and response prevention, the current standard behavioral therapy. The study aims to see if metacognitive therapy is at least as effective as the standard approach in reducing OCD symptoms. Participants will receive one of the two therapies, and their symptom changes will be measured over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Metacognitive therapy, a psychological treatment that targets unhelpful thinking patterns, compared with exposure and response prevention, a standard behavioral therapy for OCD.
- What this could lead to
- If metacognitive therapy proves as good as or better than standard exposure therapy, it could offer a new, effective treatment option for people with OCD who don't fully recover with current approaches.
- What could go wrong
- This is a relatively small trial, and the results may not apply to everyone with OCD. Metacognitive therapy is still being tested and may not be more effective than existing treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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74 people
The number who actually took part.
- Started
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Jun 2016
- Finished
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Jan 2020
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Primary diagnosis: obsessive-compulsive disorder * German-speaking * Agreeing to participate, verified by completion of informed consent * Stable medication (at least 4 weeks) Exclusion Criteria: * Current or past diagnosis of substance dependence, psychosis, neurological conditions * Mental retardation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Leipzig University
Leipzig, Germany
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Philipps University Marburg
Marburg, Germany
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