Blood clues may unlock fibromyalgia and muscle loss mystery
NCT ID NCT07381348
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at blood samples from 66 women to find differences in small molecules (metabolites) between those with fibromyalgia, those with both fibromyalgia and possible sarcopenia (muscle loss), and healthy women. The goal was to identify potential biomarkers that could help diagnose or understand these conditions better. No treatments were tested; this was purely an observational study to gather knowledge.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could point toward new biomarkers for diagnosing fibromyalgia and sarcopenia, potentially leading to earlier detection and better treatments.
- What could go wrong
- This is a small, completed observational study (66 women) that only identifies differences in blood metabolites. It does not test any treatment, so any future applications are uncertain and require much more research.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
66 people
The number who actually took part.
- Started
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Jun 2022
- Finished
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May 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Forty-four female patients aged 18-60 years and 22 healthy female controls who applied to the physical therapy outpatient clinics of Ankara City Hospital FTR hospital and were diagnosed with Fibromyalgia according to the American Rheumatology Society (ACR) 2016 diagnostic criteria.
- Ages
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18 to 60 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Being between 18-60 years old 2. Being diagnosed with Fibromyalgia according to ACR 2016 diagnostic criteria 3. Having agreed to participate in the study 4. Healthy controls 5. Being a woman Exclusion Criteria: 1. Those who cannot take command due to cognitive dysfunction 2. Pregnancy 3. Those with severe cardiac disease, COPD, malignancy, neuromuscular disease, inflammatory rheumatic disease and organ failure 4. Those with orthopedic disorders that may cause limitation in joint range of motion and/or loss of motor muscle strength 5. Patients using systemic glucocorticoid, ACE-I / ARB, statin, sulfonylurea, allopurinol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ankara Bilkent City Hospital Physical Treatment and Rehabilitation Hospital
Ankara, Ankara, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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