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New MRI technique could sharpen brain tumor diagnosis

NCT ID NCT04772456

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This early-phase study tests a special MRI technique that uses a substance called hyperpolarized pyruvate to make brain tumors easier to see. The goal is to see if this method is safe and more accurate than standard MRI for diagnosing gliomas. Up to 5 adults with suspected or known brain tumors will be scanned before surgery, and the MRI results will be compared to the actual tumor tissue analysis.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rosy Njonkou Tchoquessi

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hyperpolarized 13C-Pyruvate

What this could lead to

If successful, this could lead to a more accurate, non-invasive way to diagnose brain tumors using MRI.

What could go wrong

This is a very early, small study with only 5 people. The new imaging method may not prove more accurate than standard MRI, and safety is still being evaluated.

Conditions

The condition(s) this trial relates to.

glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.