New mesh aims to stop hernias after belly surgery

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Subject has provided informed consent. 2. Subject is ≥18 years of age at the time of consent. 3. Subject will be undergoing an elective surgery with a planned/possible midline laparotomy with retrorectus mesh placement. 3a. Subject will be undergoing an elective laparoscopy with a planned possibility of a conversion to midline laparotomy or an elective laparoscopy with a planned possible midline laparotomy for specimen extraction. Pre-Operative Exclusion Criteria: 1. Subject is undergoing emergency surgery, i.e. lifesaving procedures performed where patient is in imminent danger of death 2. Subject has a history of allergic reactions after application of poly-L-lactide, poly-trimethylene carbonate copolymers (PLLA/TMC) 3. Subject is pregnant or is planning pregnancy during study duration period (Females of child-bearing potential will be required to provide either a urine or serum pregnancy test (except for subjects who are surgically sterile or are at least 2 years postmenopausal)) 3a. Subject is breastfeeding or is planning to breastfeed during the study duration period 4. Subject is unable or unwilling to comply with the study requirements or follow-up schedule 5. Subject is scheduled for another planned surgery, and subsequent surgery would jeopardize previous application of study treatment 6. Subject with a body mass index (BMI) \> 45 kg/m2 7. Subjects with the following medical interventions/medical conditions are excluded from participation in the study: uncontrolled diabetes (hemoglobin A1c (Hb1Ac) \> 60mmol/mol), cirrhosis, stoma wearers 8. Concomitant ostomy (stoma creation or closure) 9. Subject who had received a mesh in a previous ventral hernia repair or has an existing ventral hernia \> 2 cm 10. Subject with a life expectancy inferior to the study follow-up duration (36 months) 11. Study procedure is a relaparotomy within 30 days of previous abdominal surgery 12. Subject with an American Society of Anesthesiologists (ASA) scores higher than 3 13. Subject has participated in an investigational drug study within the washout period of the drug or in a device study that would interfere with mesh implantation or assessment of Incisional Hernia 14. Subject with current chemo and/or radiation therapy within 2 weeks of procedure Only exclusion of chemotherapeutic drugs that have: * Cytotoxic effect and/or * Inhibit of cell replication and/or * Impaired tissue healing 15. Subject with any history of ascites 16. Subject has a medical condition that precludes the patient from participation in the opinion of the investigator 17. Subject is undergoing a vascular procedure other than abdominal aortic aneurysm (AAA) surgery (i.e, only AAA surgeries accepted) Intraoperative Exclusion criteria 1. Subject's study procedure is in a contaminated or infected site as assessed by the Investigator(s) (CDC Class 3 and 4) 2. Abdomen is left open at the end of the procedure 3. Subject has an unsuspected ventral hernia \>2cm encountered at the time of laparotomy 4. Inability to close the anterior fascia or keep the mesh securely out of the peritoneal cavity 5. Second-look procedure planned 6. Cases requiring a full-thickness partial resection of the abdominal wall (in particular the midline) because of involvement in neoplastic process or complex fistula 7. Inoperable tumor/poor prognostic cancer/patient non curatively treated 8. Subject has a suture length to wound length ratio\< 3.5/1 9. Subject has any ongoing infection at the time of the surgery, that is uncontrolled and/or requiring treatment such as antibiotics 10. Subject was not implanted with Deternia™ Self Gripping Resorbable Mesh 11. Subject requires more than 1 mesh