New mesh aims to stop hernias after belly surgery

NCT ID NCT05424484

Ongoing Prevention Sponsor: Medtronic - MITG Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a special mesh that dissolves over time, placed along the suture line after a midline abdominal incision. The goal is to see if it lowers the chance of developing an incisional hernia. About 123 adults having planned or possible open abdominal surgery will receive the mesh and be followed for hernia occurrence using exams and ultrasound.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Self-gripping resorbable mesh (Deternia™)
What this could lead to: If successful, this mesh could become a standard way to prevent incisional hernias after abdominal surgery, reducing the need for additional operations.
What could go wrong: This is a single-arm study with no comparison group, so benefits may be overstated. The mesh is new and long-term safety data are limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Incisional Hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INCISIONAL HERNIA INCISIONAL HERNIA OF MIDLINE OF ABDOMEN MIDLINE LAPAROTOMY

Contacts and locations

Locations

Barmherzige Brüder Regensburg

Regensburg, 93049, Germany
Cardiff and Vale University Local Health Board

Cardiff, CF14 4XW, United Kingdom
Clinical Hospital Center Sisters of Mercy

Zagreb, 10000, Croatia
Consorci Sanitari de l'Anoia Hospital Universitari d'Igualada

Igualada, Barcelona, 08700, Spain
Countess Of Chester Hospital NHS Foundation Trust

Chester, Cheshire, CH2 1HJ, United Kingdom
Hospital Universitario Ramón y Cajal

Madrid, 28034, Spain
Hospital Universitario Virgen Macarena

Seville, 41009, Spain
Hospital de la Santa Creu i Sant Pau

Barcelona, 08041, Spain
IJsselland Ziekenhuis

Capelle aan den IJssel, Netherlands
Klinikum Braunschweig

Braunschweig, 38118, Germany
Maastricht University Medical Center

Maastricht, 6229, Netherlands
Pius-Hospital Medical Campus University of Oldenburg

Oldenburg, 26121, Germany
University Hospital Center of Zagreb

Zagreb, 10000, Croatia

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