Menthol E-Cigs under the microscope: do they boost nicotine addiction?
NCT ID NCT05338801
First seen Apr 03, 2026 · Last updated Jun 23, 2026 · Updated 16 times
Summary
This study looks at how menthol flavor in e-cigarettes affects young users' nicotine dependence, puffing habits, and exposure to harmful chemicals. Researchers will have 250 participants aged 21-35 use both menthol and tobacco-flavored e-cigarettes in lab sessions. The goal is to provide evidence for the FDA on whether menthol should be regulated to reduce e-cigarette harm.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Florida International University
RECRUITINGMiami, Florida, 33199, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Menthol-flavored e-cigarette liquid
What this could lead to
If successful, this study could help regulators understand whether menthol flavoring in e-cigarettes increases addiction and health risks, guiding future policies to reduce harm.
What could go wrong
This is an observational lab study, not a treatment trial. Results may not reflect real-world use, and the findings are preliminary—they won't directly change clinical practice.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.