Massive new registry to track menopause health in 5,000 women

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\. Age: women aged 18-60 years at the time of enrollment and in follow up, up to 65 years old * 2\. Women in Perimenopause, defined as the transitional period preceding the final menstrual period, characterized by changes in menstrual cycle regularity and/or the onset of menopausal symptoms. Women experience variable cycle length, skipped cycles, or amenorrhea of less than 12 months' duration, often accompanied by vasomotor symptoms, sleep disturbances, and other menopause-related complaints. * 3\. Women in Menopause, defined as the permanent cessation of menstruation resulting from loss of ovarian follicular activity and is diagnosed retrospectively after 12 consecutive months of amenorrhea in the absence of other pathological or physiological causes. Women may present with persistent menopausal symptoms and/or long-term consequences of estrogen deficiency, including changes in bone, cardiovascular, metabolic, and genitourinary health. lt includes women in early Menopause, defined as menopause occurring before the age of 45 years, but after 40 years, in the absence of surgical or iatrogenic causes. * 4\. Women in Premature Ovarian lnsufficiency (POI), defined as impaired ovarian function occurring before the age of 40 years, characterized by oligo- or amenorrhea, elevated gonadotropin levels, and hypoestrogenism. * 5\. Women with iatrogenic menopause, caused by: * Bilateral oophorectomy * Chemotherapy or radiotherapy-induced ovarian failure * Other pharmacological treatments resulting in ovarian insuftficiency * 6\. Women evaluated at the specialized Menopause Clinic or the Multidisciplinary Endocrinology/Metabolic Disorders clinic. * 7\. Data availability: for retrospective participants, sufficient medical records must be available; tor prospective participants, patients must be willing to participate in the registry and provide informed consent. * 8\. All women are eligible regardless of concomitant diseases, to reflect real-world clinical practice. Exclusion Criteria: * 1\. Women unable to provide informed consent due to cognitive impairment or severe psychiatric conditions. * 2\. Women already participating in interventional clinical trials affecting menopausal or metabolic management in a way that could bias observational data. * 3\. Women with incomplete medical records for retrospective data collection or those refusing informed consent for prospective enrollment.