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Can a common Alzheimer's drug clear lupus brain fog?

NCT ID NCT03527472

First seen Feb 10, 2026 · Last updated May 23, 2026 · Updated 15 times

Summary

This study tested whether memantine, a drug used for Alzheimer's, can improve thinking and memory problems in people with lupus. 111 adults with lupus and cognitive issues took either memantine or a placebo for 14 weeks. The goal was to see if the drug could safely ease brain fog symptoms in a specific group of lupus patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • The University of Texas Health Science Center, Houston

    Houston, Texas, 77030, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.