Can a common Alzheimer's drug clear lupus brain fog?

NCT ID NCT03527472

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether memantine, a drug used for Alzheimer's, can help with thinking and memory problems in people with lupus. About 111 adults with lupus and cognitive issues took either memantine or a placebo for 14 weeks. The goal was to see if the drug safely improves brain function in this specific group.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • The University of Texas Health Science Center, Houston

    Houston, Texas, 77030, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

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