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Melatonin boosts dental implant success, study finds

NCT ID NCT07374523

Disease control Sponsor: Suez Canal University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether applying melatonin to dental implants helps them fuse more firmly with the jawbone. Sixteen adults with a single missing lower tooth received an implant with or without melatonin. Researchers measured implant stability and pain levels after the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

16 people

The number who actually took part.

Started

Sep 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients aged between 21 and 60 years. 2. Good general health (ASA I). 3. Non-smokers or light smokers (\<10 cigarettes/day). 4. Presence of a single non-restorable mandibular tooth indicated for extraction (incisor, canine, or premolar). 5. Adequate bone volume to receive a dental implant. 6. Patients with good oral hygiene. Exclusion Criteria: 1. Medically compromised patients (e.g., uncontrolled diabetes, immunosuppressive therapy, bisphosphonate use) 2. Pregnant and lactating women. 3. Active periodontal disease at the implant site. 4. Acute infection at the extraction site (abscess or sinus tract). 5. Severe parafunctional habits (e.g., bruxism, clenching).

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Implant therapy

Contacts and locations

Locations

  • Faculty of Dentistry Suez Canal University

    Ismailia, Egypt, Egypt

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