Melanoma therapy may impact fertility – new study investigates
NCT ID NCT05429138
First seen Nov 18, 2025 · Last updated Jun 22, 2026 · Updated 29 times
Summary
This study tracks fertility markers in 80 melanoma patients (women aged 18-37, men aged 18-45) before, during, and after adjuvant therapy with anti-PD-1 or targeted treatments. Researchers measure hormone levels in women and sperm quality in men to see how these change over time. The goal is to better understand the effects of modern melanoma treatments on reproductive health.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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AP-HM
RECRUITINGMarseille, France
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APHP- Ambroise Paré
RECRUITINGParis, France
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APHP-Cochin
RECRUITINGParis, France
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APHP-Saint Louis
RECRUITINGParis, France
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CHRU de Nîmes
RECRUITINGNîmes, France
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CHU Montpellier
RECRUITINGMontpellier, France
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CHU NICE L'archet
RECRUITINGNice, France
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CHU de Bordeaux
RECRUITINGBordeaux, France
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CHU de Nantes
RECRUITINGNantes, France
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Hôpital Saint-Joseph
RECRUITINGMarseille, France
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Institut Gustave Roussy
RECRUITINGVillejuif, France
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Oncôpole de Toulouse
RECRUITINGToulouse, France
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors understand how melanoma treatments impact fertility, guiding future family planning advice for patients.
What could go wrong
This is an observational study, not a treatment trial. It only measures changes and does not test any new therapy or intervention.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.