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New combo aims to control Hard-to-Treat melanoma

NCT ID NCT03131908

First seen Jan 11, 2026 · Last updated May 01, 2026 · Updated 18 times

Summary

This study tests whether adding an experimental drug (GSK2636771) to an approved immunotherapy (pembrolizumab) can help control metastatic melanoma that has not responded to prior treatment. It is for patients whose tumors have a specific genetic change called PTEN loss. Up to 41 participants will receive the combination to find the best dose and see how well it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.