Drug combo tested to shrink tumors before melanoma surgery
NCT ID NCT04221438
Summary
This study tested whether giving two targeted drugs (encorafenib and binimetinib) before surgery could help shrink melanoma tumors in patients whose cancer had spread to nearby lymph nodes. The drugs work by blocking specific signals that help cancer cells grow. The trial also explored whether a special imaging scan could predict how well patients would respond to the treatment. The study was terminated early after enrolling only 3 participants.
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Contacts and locations
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Locations
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Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111, United States
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Los Angeles County-USC Medical Center
Los Angeles, California, 90033, United States
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Siteman Cancer Center at Christian Hospital
St Louis, Missouri, 63136, United States
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Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters, Missouri, 63376, United States
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Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri, 63141, United States
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Siteman Cancer Center-South County
St Louis, Missouri, 63129, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109, United States
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University of Wisconsin Carbone Cancer Center
Madison, Wisconsin, 53792, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
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