New hope for kids with rare brain tumor: targeted pill shows promise
NCT ID NCT05286788
First seen Jan 12, 2026 · Last updated May 23, 2026 · Updated 28 times
Summary
This study tests an oral drug called MEKTOVI (binimetinib) in children and young adults (ages 1 to 39) with a rare brain tumor called adamantinomatous craniopharyngioma that has come back or grown after treatment. The drug works by blocking certain signals that help tumors grow. The main goal is to see if the drug can shrink or control the tumor. This is a Phase 2 trial with 38 participants.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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British Columbia Children's Hospital
RECRUITINGVancouver, British Columbia, V6H 3N, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Sainte-Justine
RECRUITINGMontreal, Quebec, Canada
Contact Email: •••••@•••••
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Children's Hospital Colorado
RECRUITINGAurora, Colorado, 80045, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Children's National Medical Center
RECRUITINGWashington D.C., District of Columbia, 20010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nationwide Children's Hospital
RECRUITINGColumbus, Ohio, 43205, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nicklaus Children's Hospital
RECRUITINGMiami, Florida, 33155, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Perth Children's Hospital
RECRUITINGPerth, Western Australia, 6000, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Queensland Children's Hospital
RECRUITINGSouth Brisbane, Queensland, 4101, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sydney Children's Hospital
RECRUITINGRandwick, New South Wales, 2031, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.