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Mediterranean diet tested for brain and body benefits in seniors

NCT ID NCT06287489

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed trial tested whether a 3-month Mediterranean diet could improve thinking and physical abilities in 57 older adults who feel their memory is slipping but still score normally on tests. Participants ate either a Mediterranean diet or their usual diet, then switched. Researchers used brain scans and blood tests to explore how the diet might work.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mediterranean diet
What this could lead to
If it works, this could point toward a simple dietary approach to help maintain thinking and physical abilities in older adults worried about memory decline.
What could go wrong
This is a small, completed trial with only 57 participants. The diet lasted only 3 months, so any benefits may be short-lived or not apply to everyone. Results are not yet published.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

57 people

The number who actually took part.

Started

Oct 2023

Finished

Dec 2024

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Subjective cognitive decline (SCD)-plus subjects, individuals must meet five criteria: 1. Subjective memory decline without impairment in other cognitive domains (MMSE \> 26; MMSE \> 14 for \<6 years of education). 2. Onset of subjective cognitive decline within the past 5 years. 3. Age at the onset of subjective cognitive decline is \>60 years. 4. Concern and preoccupation with memory decline. 5. Perceived functional decline relative to peers and meet one of three criteria: a. Caregiver perceives cognitive decline; b. Carries APOE ε4 genotype; c. Clinical evidence of preclinical Alzheimer's disease biomarkers. Exclusion Criteria: Exclude individuals who: 1. Cannot comply with or accept the dietary intervention (e.g., dietary restrictions, vegetarianism, lactose intolerance). 2. Have walking speed ≤ 0.3 meters/second. 3. Have significant medical conditions affecting physical and cognitive functions. 4. Have chronic kidney disease (eGFR \<30 ml/min/1.73m2) or undergo dialysis. 5. Experience poorly controlled cardiovascular diseases or malignant tumors. 6. Have severe visual and hearing impairments preventing assessments. 7. Have undergone hormone therapy in the preceding three months or are expected to during the trial.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

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