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Meditation may rewire the brain and heat the body — a brain-scanning study puts it to the test.

NCT ID NCT01262404

Knowledge-focused Sponsor: Boston University Charles River Campus Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This study investigates whether different types of meditation can alter brain structure and function. Healthy adults will be trained in mindfulness meditation, compassion meditation, or a health education class, and undergo brain scans before and after training. A separate group of experienced Tibetan gtummo meditators will have their body temperature mapped with MRI during the practice. The goal is to see if compassion meditation produces the largest brain changes and whether gtummo meditation can measurably raise body temperature.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
mindfulness meditation, compassion meditation, and Tibetan gtummo meditation
What this could lead to
If it works, this could reveal how different meditation practices physically reshape the brain and alter body temperature, pointing toward new ways to manage stress.
What could go wrong
This is an early imaging study with a small number of participants. Brain changes may be subtle or not appear at all, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

58 people

The number who actually took part.

Started

Jan 2010

Finished

Oct 2011

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Community Sample

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-65 for the mindfulness-compassion study * Prior training in gtummo meditation for the gtummo study Exclusion Criteria: * Previous experience with meditation for the mindfulness-compassion study

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stress

Contacts and locations

Locations

  • Boston University Dept. of Cognitive and Neural Systems

    Boston, Massachusetts, 02215, United States

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