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Brain zapping trial maps current paths in epilepsy patients

NCT ID NCT02263274

Knowledge-focused Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study used 30 epilepsy patients who already had electrodes implanted in their brains for surgery planning. Researchers applied a mild electrical stimulation called tDCS and measured exactly how the current spread. The goal was to improve computer models that predict where the electricity goes, which could help design better brain stimulation treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transcranial Direct Current Stimulation (tDCS)
What this could lead to
If successful, this could lead to more precise tDCS targeting for brain stimulation therapies in conditions like depression or epilepsy.
What could go wrong
This is a small, early-stage measurement study, not a treatment trial. The stimulation levels are very low and not expected to change brain function, so direct patient benefits are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Nov 2013

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Subjects for this study will be recruited from patients undergoing routine intracranial electrode placement as part of the evaluation for surgical treatment of medically refractory epilepsy. Inclusion criteria include: 1. Age ≥ 18 years 2. Placement of intracranial electrode arrays (grid, strip and or depth electrodes) for seizure focus localization and/or mapping of eloquent cortex 3. Able to provide written informed consent 4. English-speaking patients only Exclusion Criteria: 1. Cognitive impairment (Intelligence Quotient \<70) 2. Facial or forehead skin breakdown that would interfere with surface electrode placement 3. Contraindication to MRI 4. Known adhesive allergy 5. Space occupying intracranial pathology including brain tumor, ateriovenous malformation, cavernous malformation, prior surgical resection or significant encephalomalcia that would create unknown tissue inhomogeneity that cannot be accurately modeled. 6. Subjects who have had an electrographic or clinical seizure within one hour prior to the stimulation procedure

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Conditions

The condition(s) this trial relates to.

epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Epilepsy

Contacts and locations

Locations

  • Neurology

    New York, New York, 11106, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.