Stem cell hope for bone marrow disease
NCT ID NCT03184935
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether stem cells from donated umbilical cords are safe and can help people with myelodysplastic syndrome (MDS), a bone marrow disorder. About 40 participants with moderate to severe symptoms will receive the stem cells and be monitored for side effects and improvement. The study is currently on hold.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * MDS patients with international prostate symptom score is moderate or severe symptoms Exclusion Criteria: * with serious renal function impaired * with other organ function abnormal: acute hepatitis B, ejection fraction \< 40%, serum bilirubin \> 3mg/dl, liver function tests abnormal, central nervous system disease, mental disease * bad physical condition (Karmofsky \< 60%) * without signing informed consent form * under other therapy that possibly influence MSC security or efficacy * HIV or other serious disease infection * Donor: HIV, active hepatitis B/C infection, Syphilitic antibody positive * Donor/ participants: alcoholism, drug addicted, mental disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Inner Mongolia International Mongolian Hospital
Hohhot, Inner Mongolia, 010065, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can starting anemia drug sooner keep MDS patients off transfusions?
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- New drug combination targets Hard-to-Treat blood cancers
- Can a calming drug make cord blood transplants safer?
- Can a Three-Drug combo shield stem cell transplant patients from a dangerous immune attack?