Magnetocardiography may cut unnecessary heart procedures
NCT ID NCT07341932
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a non-invasive heart scan called magnetocardiography (MCG) can help doctors decide the best treatment for people with stable coronary artery disease. About 1,300 participants with moderate blockages will be randomly assigned to either MCG-guided care or standard care. The goal is to see if MCG reduces unnecessary invasive procedures while maintaining safety and quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,312 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 18-80 years, regardless of gender. 2. Patients with stable coronary artery disease (CAD). 3. Coronary computed tomography angiography (CCTA) shows at least one major coronary vessel (diameter ≥2.5 mm) with 50-90% stenosis. Patients with 50-69% stenosis must have typical or atypical angina; for those with 70-90% stenosis, the presence of chest pain symptoms is not required. \*Note: Chest pain is characterized by the following three features:\* \*(1) Chest discomfort lasting less than 15 minutes;\* \*(2) Precipitated by physical exertion or emotional stress;\* \*(3) Relieved by rest or nitrates.\* \*Based on these, angina is classified as:\* * \*Typical angina: all 3 features are present;\* * \*Atypical angina: 2 features are present;\* * \*Non-anginal chest pain: 1 or no feature is present.\* 4. Willing to participate in the study and provide written informed consent. Exclusion Criteria: 1. Previous myocardial infarction, PCI, CABG, or coronary angiography indicating stenosis ≥50% in a major vessel. 2. CCTA indicating left main coronary artery stenosis \>50% and/or three-vessel disease. 3. History of cardiac dysfunction (≥ NYHA Class III), severe congenital heart disease, valvular heart disease, or cardiomyopathy. 4. Complex arrhythmias, such as frequent atrial premature beats, ventricular premature beats, atrial fibrillation, atrial flutter, etc. 5. History of metal implant placement (including mechanical valves, pacemakers, orthopedic internal fixation plates, drug pumps, etc.). 6. Claustrophobia. 7. Severe thoracic deformity. 8. Active bleeding. 9. Any disease with an expected survival of less than 1 year. 10. Completion of any of the following tests prior to enrollment: exercise ECG, stress echocardiography, stress SPECT, or stress CMR. 11. Any other condition where the investigator considers the patient unsuitable for this study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Air Force Medical Center, People's Liberation Army of China
NOT_YET_RECRUITINGBeijing, Beijing Municipality, China
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Beijing United Family Hospital
RECRUITINGBeijing, Beijing Municipality, China
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The Third People's Hospital of Chengdu
NOT_YET_RECRUITINGChengdu, Sichuan, China
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Urumqi Friendship Hospital
NOT_YET_RECRUITINGÜrümqi, Xinjiang Uygur Autonomous Region, China
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首都医科大学附属北京安贞医院
RECRUITINGBeijing, Beijing Municipality, China
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