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Engineered immune cells take on tough blood cancers in early trial

NCT ID NCT03853616

First seen Jan 04, 2026 · Last updated May 22, 2026 · Updated 25 times

Summary

This early-stage trial tests a new treatment called MB-CART19.1, which uses a patient's own immune cells that are modified in a lab to better find and attack cancer cells. It is for children and adults with certain blood cancers (like leukemia or lymphoma) that have returned or not responded to standard therapy. The main goal is to find the safest dose and see if the approach is feasible.

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Contacts and locations

Locations

  • Charité - University clinic, pediatric clinic with focus on oncology and hematology

    Berlin, 13353, Germany

  • Children's Hospital of Dr. von Hauner by Ludwig-Maximilian University

    Munich, 80337, Germany

  • Tuebingen University clinic, medical university clinic for internal medicine

    Tübingen, 72076, Germany

  • University clinic for children and youth medicine

    Tübingen, 72076, Germany

  • University clinic, pediatric hematology and oncology

    Würzburg, 97070, Germany

  • University medicine Goettingen, Clinic of hematology and medical oncology

    Göttingen, 37075, Germany

  • Universitätsklinikum Erlangen

    Erlangen, 91054, Germany

  • Universitätsklinikum Münster - Klink für Kinderheilkunde und Jugendmedizin / Pädiatrische Hämatologie und Onkologie

    Münster, 48149, Germany

  • Universitätsklinikum Münster - Medizinische Klinik A / KMT Zentrum

    Münster, 48149, Germany

Conditions

Explore the condition pages connected to this study.