Engineered immune cells take on tough blood cancers

NCT ID NCT03853616

First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 24 times

Summary

This early-stage trial tests a new treatment called MB-CART19.1 for people whose B-cell blood cancers (like leukemia or lymphoma) have returned or stopped responding to standard therapy. The treatment uses a patient's own immune cells, modified to better recognize and attack cancer cells. The main goal is to find the safest dose and see if the approach is feasible in about 48 adults and children.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for B-CELL LYMPHOMA REFRACTORY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Charité - University clinic, pediatric clinic with focus on oncology and hematology

    Berlin, 13353, Germany

  • Children's Hospital of Dr. von Hauner by Ludwig-Maximilian University

    Munich, 80337, Germany

  • Tuebingen University clinic, medical university clinic for internal medicine

    Tübingen, 72076, Germany

  • University clinic for children and youth medicine

    Tübingen, 72076, Germany

  • University clinic, pediatric hematology and oncology

    Würzburg, 97070, Germany

  • University medicine Goettingen, Clinic of hematology and medical oncology

    Göttingen, 37075, Germany

  • Universitätsklinikum Erlangen

    Erlangen, 91054, Germany

  • Universitätsklinikum Münster - Klink für Kinderheilkunde und Jugendmedizin / Pädiatrische Hämatologie und Onkologie

    Münster, 48149, Germany

  • Universitätsklinikum Münster - Medizinische Klinik A / KMT Zentrum

    Münster, 48149, Germany

Conditions

Explore the condition pages connected to this study.