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Promising ALS drug combo heads to final phase 3 trial

NCT ID NCT07174492

First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 30 times

Summary

This phase 3 trial tests whether adding masitinib to standard ALS treatment (riluzole) can slow the loss of physical function better than placebo plus riluzole. About 412 adults with ALS will take the drug or placebo for 48 weeks. The main goal is to measure changes in daily abilities using the ALSFRS-R scale, which tracks movement, breathing, and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aiginition Hospital

    Athens, Greece

    Contact

Conditions

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