Could a Hands-On therapy help diabetic nerve pain and blood sugar?
NCT ID NCT07537270
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested whether two types of manual therapy (nerve mobilization and neck-based techniques) could help control blood sugar and reduce pain in 75 adults with diabetic peripheral neuropathy. Participants received twice-weekly sessions for 12 weeks, and the study focused on whether such a trial is feasible. While the main goal was to see if a larger study could be done, researchers also looked at changes in blood sugar levels and pain intensity.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Manual neural mobilization and cervical neuromodulatory techniques (manual therapy procedures)
- What this could lead to
- If this pilot shows promise, it could point toward a drug-free way to help manage blood sugar and nerve pain in people with diabetic neuropathy.
- What could go wrong
- This is a very small, early pilot study focused on feasibility, not proof of effectiveness. The results may not be generalizable, and any benefits seen could be due to chance or placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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75 people
The number who actually took part.
- Started
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Feb 2026
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Clinically confirmed diabetic peripheral neuropathy * Ability to attend twice-weekly intervention sessions for 12 weeks * Stable medication regimen for at least 3 months Exclusion Criteria: * Severe cardiovascular, neurological, or musculoskeletal disorders * Recent surgery (\<6 months) in lower limbs or cervical spine * Pregnancy or breastfeeding * Cognitive impairment preventing informed consent or compliance
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cairo University Hospitals, Kasr Al-Ainy
Cairo, Egypt
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Other studies related to the condition(s) this trial covers.