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New combo therapy shows promise for rare blood cancer

NCT ID NCT03863184

First seen Apr 29, 2026 · Last updated Jun 16, 2026 · Updated 11 times

Summary

This study tests a combination of three drugs (acalabrutinib, lenalidomide, and either rituximab or obinutuzumab) in people with untreated mantle cell lymphoma, a rare blood cancer. About 37 adults will receive the treatment for one year, then continue on a lower dose to keep the cancer from coming back. The goal is to see if the combination can make the cancer disappear completely at a microscopic level.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Weill Cornell Medicine

    New York, New York, 10065, United States

Conditions

The condition(s) this trial relates to.

mantle cell lymphoma Neoplasm, Residual

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.