Jaw reconstruction study: are immediate dental implants as accurate in delayed cases?
NCT ID NCT07452315
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial looks at how accurately surgeons can rebuild the lower jaw using a bone flap from the leg, combined with custom plates and immediate dental implants. It compares fresh cases (right after removing diseased tissue) with delayed cases (where the defect already exists). Twenty-two adults will have CT scans before and after surgery to check how well the reconstruction matches the virtual plan.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- fibula free flap with patient-specific plates and immediate dental implants
- What this could lead to
- If successful, this could show that immediate dental implants during jaw reconstruction are as accurate in delayed cases as in fresh ones, improving surgical planning.
- What could go wrong
- This is a small, non-randomized trial with only 22 participants, so results may not apply widely. Accuracy measurements may not translate to better long-term outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 22 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Jan 2026
- Expected to finish
-
Jan 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria for participants: * Adult patients with conditions requiring mandibular reconstruction using fibula free flaps. * Adult patients diagnosed with neoplastic conditions requiring resection and agreed to immediate reconstruction * Adult patients with segmental mandibular defects resulting from previous pathology, trauma, infectious conditions * Patients willing for the surgical procedure and follow-up, with an informed consent. Exclusion Criteria for participants: * Patients with significant medical diseases and comorbidities preventing them undergoing lengthy procedures under general anesthesia * Patients with Peripheral Vascular Disease * Patient with known allergy to contrast media in whom a CTA of the lower limbs will not be possible * Patients with Peronea Magna where the peroneal artery is the main blood supply of the lower limbs and its harvesting might result in compromise of the leg vascularity * Patients with no desire for surgical correction * Patients with any diseases that compromise bone or soft tissue healing. Patients with local pathosis that interfere with the bone healing.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Mandible reconstruction are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Oral and dental medicine
Giza, الجيزة, 12611, Egypt