Magnetic pulses to the neck reveal how the diaphragm works
NCT ID NCT05302752
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This study tests a method to measure diaphragm muscle function using rapid magnetic stimulation of the phrenic nerves in the neck. Researchers will check how repeatable the measurements are and how adding weights to the chest affects breathing. Sixteen healthy, non-smoking adults with normal lung function will take part. The goal is to better understand diaphragm contractility, which could help assess respiratory muscle health in future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- magnetic phrenic nerve stimulation
- What this could lead to
- If successful, this could improve methods for assessing diaphragm function in health and disease.
- What could go wrong
- This is a small, early-stage study in healthy volunteers only, so results may not apply to patients with respiratory conditions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
16 people
The number who actually took part.
- Started
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Jul 2022
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 39 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * healthy * non-smoking * normal lung function * body mass index: 18.5-29.9 kg/m2 * able to communicate in english * willing to adhere to study rules Exclusion Criteria: * acute illness or chronic conditions of the gastrointestinal tract, and health conditions affecting metabolism, the cardiovascular or the respiratory system, or sleep * intake of medications affecting metabolism, the cardiovascular, the neuromuscular or the respiratory system, or sleep * any metal or electronics inside of the body * presence of cardiac pacemaker, implanted defibrillators or implanted neurostimulators * history of seizures or epilepsy * tatoos on the stimulation sites * previous enrolment in this study * for women: pregnancy, breastfeeding, or intention to become pregnant during the study
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Exercise Physiology Lab, Institute of Human Movement Sciences and Sport, ETH Zurich
Zurich, Canton of Zurich, 8092, Switzerland
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