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Simple spray before surgery may soothe sore throat and stress

NCT ID NCT06091631

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether inhaling magnesium sulfate before surgery could reduce sore throat and stress caused by breathing tubes. One hundred adults having gallbladder surgery were included. Researchers measured sore throat at several time points and checked heart rate, blood pressure, and blood sugar to see if stress improved.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
magnesium sulfate
What this could lead to
If it works, this could offer a simple, low-cost way to reduce sore throat and stress after anesthesia.
What could go wrong
This is a small, completed study with no phase designation, so results may not apply broadly. Magnesium sulfate can cause side effects like low blood pressure or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Nov 2023

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 20-50 years old * ASA: 1, 2 * Elective fit laparoscopic cholecystectomy Exclusion Criteria: * -Patient refusal * patients with history of hypersensitivity to magnesium sulphate * patients with coronary ischemic disease, atrioventricular block of any degree, known cardiac arrhythmias, heart failure * on beta blockers or calcium channel blockers * expected difficult intubation (Mallampati 4) * Body mass index \> 40

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia complication Anesthesia intubation complication

Contacts and locations

Locations

  • Assiut university, faculty of medicine, anesthesia and ICU and pain management department

    Asyut, Asyut Governorate, 71515, Egypt

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