Magnesium may tame perimenopause symptoms, small trial hopes
NCT ID NCT07235878
First seen Jun 26, 2026 · Last updated Aug 06, 2026 · Updated 3 times
Summary
This study tests whether taking magnesium supplements for 12 weeks can help with common perimenopause symptoms like hot flushes, sleep problems, mood swings, and brain fog. Researchers will give 58 women either magnesium or a placebo pill daily and measure changes in memory, sleep, and quality of life. The goal is to see if this simple supplement offers real relief during the menopause transition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- magnesium hydroxide (a dietary supplement)
- What this could lead to
- If it works, this could point toward a simple, non-hormonal option to help with perimenopause symptoms like sleep trouble and memory issues.
- What could go wrong
- This is a small, early-stage trial with only 58 women, so results may not apply to everyone. Magnesium supplements are generally safe but can cause stomach upset in some people.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 58 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 60 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Self-assess as healthy * Report experiencing troublesome peri-menopause symptoms in the past 6 months but not post-menopausal (defined as 12 months with no periods) Exclusion Criteria: * Post-menopausal * Lactating, pregnant or seeking to become pregnant * Nut Allergy * Taken antidepressant/antianxiety medication or other medication with strong likelihood for effects on cognition or sleep in the past 6 months. * Habitual magnesium supplementation (defined as more than 3 consecutive days or 4 days in total). Will be excluded unless washout for 1 month. * Menopause symptoms have been medically induced. * Receiving gender-affirming hormone therapy.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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School of Psychology, Northumbria University
Newcastle upon Tyne, NE1 8ST, United Kingdom
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