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Magnesium may boost jaw expansion and cut pain in new trial

NCT ID NCT07309640

Symptom relief Sponsor: Universiti Sains Malaysia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 17, 2026 · Updated 2 times

Summary

This study tests if taking magnesium supplements can improve a jaw-widening treatment called Alt-RAMEC for adults aged 18-30 with a narrow upper jaw. Participants will either get the treatment alone or with magnesium. Researchers will measure changes in jaw structure and muscle activity, and track pain levels. The goal is to see if magnesium makes the treatment work better and feel less uncomfortable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

38 people

The number who actually took part.

Started

Jan 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion Criteria 1. All participants were young adults, from the 18- 25 age group (males or females). 2. There is a maxillary skeletal deficiency in every patient. (Anteroposterior deficiency, transverse bilateral/unilateral deficiency) 3. All teeth erupted without any abnormalities in term of shape and size. 4. Good oral hygiene and non-smoking habits. Exclusion Criteria: 1. History of previous orthodontic treatment or maxillary expansion 2. Patients with severe progressive periodontal disease 3. Patients with severe craniomaxillofacial deformities such as cleft lip and palate 4. Mid palatal fusion without successful expansion 5. First molar absent or impacted in the patient. 6. Patients who have bone loss, gingival recession, or persistent gingival inflammation. 7. Individuals with a high gag reflex. 8. History of a life-threatening medical condition, such as diabetes mellitus, or a chronic disease such as organ transplant rejection or cancer in patients receiving chemotherapy or radiation therapy and high risk of infections.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Magnesium during orthodontic expansion Orthodontic patients indicated for maxillary expansion

Contacts and locations

Locations

  • Dr. Aws Fakhri Alfatlawi specialized Orthodontics Clinic

    Baghdad, Al-Batawen, 10001, Iraq