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Can Omega-3 supplements clear the fog? new trial investigates

NCT ID NCT06695910

Symptom relief Sponsor: Samuel Fortin Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special form of omega-3 (MAG-EPA) can help people who regularly experience brain fog—symptoms like mental fatigue, poor concentration, and confusion. Researchers will give 48 adults either the supplement or a placebo for up to 112 days and track changes using a brain fog questionnaire. The goal is to see if this supplement can improve cognitive health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
omega-3 monoglycerides (MAG-EPA)
What this could lead to
If it works, this could point toward a dietary supplement option to help reduce brain fog and improve mental clarity.
What could go wrong
This is a small, early-phase exploratory study with only 48 participants. Results may not apply to everyone, and the supplement may show no benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Participant between 19 and 55 years of age. 2. Participant who reports having mental fatigue and/or frequent memory loss and/or difficulty concentrating and/or inattention, confusion and/or a feeling of decreased cognitive acuity for at least 28 days at the time of selection. 3. Participant who obtains a mean score on the BFS screening questionnaires (BFS1 and BFS2) total of at least 30 and/OR who obtains the following minimum score on at least one of the three factors: Factor 1 of at least 15 and/or Factor 2 of at least 15 and/or Factor 3 of at least 12. 4. Available for the entire duration of the study and willing to participate based on the information provided in the ICF duly read and signed by the latter. 5. Absence of intellectual problems likely to limit the validity of consent to participate in the study or the compliance with protocol requirements, ability to cooperate adequately, ability to understand and observe the instructions of the research staff. 6. Participant having no difficulty in swallowing tablets, capsules or gelcaps. Exclusion Criteria: 1. Known allergy or intolerance to fish or history of allergic reactions attributable to fish, or to a compound similar to fish oil. 2. Participant who has used omega-3 supplements in the 30 days preceding day 1 of the study. 3. Pregnant or breastfeeding woman as declared by the latter. 4. Presence of dependence on drugs of abuse or alcohol (˃ 3 units of alcohol per day, acute or chronic excessive consumption). 5. Participant included in another clinical study and who is receiving an investigational product or other research treatment.

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Conditions

The condition(s) this trial relates to.

Mental Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain fog Cognitive health

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Institut de recherche clinique du littoral (IRCL)

    RECRUITING

    Maria, Quebec, G0C 1Y0, Canada

  • Institut de recherche clinique du littoral (IRCL)

    RECRUITING

    Rimouski, Quebec, G0K 1P0, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.