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New hope for chest pain without blocked arteries? early trial tests macitentan

NCT ID NCT07392281

First seen Feb 06, 2026 · Last updated Jun 16, 2026 · Updated 15 times

Summary

This study tests a drug called macitentan in 40 adults with chest pain that isn't caused by blocked arteries (non-obstructive angina). The goal is to see if the drug improves blood flow in the tiny heart vessels and reduces chest pain. Participants will take macitentan for 4 weeks and have heart function tests and blood samples taken to understand how the drug works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • China-Japan Friendship Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100029, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

coronary microvascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.