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AI could make heart attack risk detection safer and smarter

NCT ID NCT04193475

Knowledge-focused Sponsor: Hull University Teaching Hospitals NHS Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to improve how doctors interpret stress echocardiograms—ultrasounds of the heart during exercise—by using machine learning. Researchers will analyze data from 1,250 patients to develop more accurate tools for detecting blocked arteries and heart attack risk. The goal is to reduce the need for invasive follow-up tests and help doctors choose the best treatment for each patient.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could make stress echocardiograms more accurate, helping doctors identify heart disease risk earlier and reducing the need for invasive procedures.
What could go wrong
This is an observational study developing new analysis methods, not testing a treatment. The machine learning tools may not prove reliable enough for routine clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2019

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients will be recruited into this study as a single group, with an age range of 20 - 89 years and with no restriction according to their pre-test probabilities of coronary artery disease. They will be eligible for inclusion so long as they have chest pain or another clinical indication for stress testing.

Ages

20 to 89 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinically suitable for stress echocardiography examination Exclusion Criteria: * None

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Conditions

The condition(s) this trial relates to.

Angina Pectoris cardiovascular disorder Chest Pain coronary artery disorder myocardial ischemia Sprains and Strains

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular diseases Ischaemic heart disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Castle Hill Hospital

    RECRUITING

    Cottingham, HU165JQ, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.