Lymphedema surgery study aims to see if going under the knife boosts quality of life
NCT ID NCT03248310
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study follows 600 people with lymphedema to compare quality of life between those who choose surgery (a lymph node transfer) and those who choose non-surgical management. Participants fill out questionnaires about their symptoms and daily life over time. The goal is to understand which approach leads to better long-term outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If this study shows that surgery improves quality of life more than non-surgical care, it could help guide treatment decisions for people with lymphedema.
- What could go wrong
- This is an observational study, not a controlled trial, so results may be influenced by patient choice rather than the treatment itself. It is also limited to English-speaking participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 600 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Aug 2017
- Expected to finish
-
Aug 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who present for consultation of their lymphedema and who meet eligibility criteria will be offered the option of enrolling in this study at the time of their initial consultation.
- Ages
-
18 to 80 years
- Sex
-
Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18-80 years * Primary and secondary lymphedema of the upper or lower extremity * International Society of Lymphology (ISL) Stage 1, 2, or 3 lymphedema * Proficiency in English language Exclusion Criteria: * Patients with clotting disorders, venous insufficiency, end-stage lymphedema unless they are on the non-surgical arm. * Additionally, if the patient refuses to complete questionnaires, the patient will be excluded from the study and replaced at the discretion of the principal or co-principal investigator.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Lymphedema are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
3 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
-
Memorial Sloan Kettering Nassau (Limited Protocol Activites)
RECRUITINGRockville Centre, New York, 11553, United States
-
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
RECRUITINGHarrison, New York, 10604, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could gut bacteria predict infection risk in lymphedema?
- Could online therapy ease the swelling of breast cancer lymphedema?
- Ultrasound could uncover hidden vascular risks in turner syndrome
- Can swollen limbs throw off your balance? a study investigates
- Could reapplying compression bandages three times a day beat the standard Once-Daily treatment for lymphedema?
- New study aims to catch lymphedema early in breast cancer patients