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New surgery aims to stop lymphedema before it starts

NCT ID NCT06650592

Prevention Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a surgical technique called immediate lymphatic reconstruction (ILR) done at the same time as lymph node removal for cancer. The goal is to reconnect tiny lymph channels to nearby veins to prevent lymphedema, a painful arm swelling. Researchers will measure arm size and use special devices to see if ILR works. They will also explore how skin bacteria might affect lymphedema risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Immediate lymphatic reconstruction (ILR) surgery
What this could lead to
If successful, this could provide strong evidence that ILR prevents lymphedema after lymph node removal, potentially making it a standard preventive procedure.
What could go wrong
This is an early-stage, single-center study with only 90 participants. The surgery is new and not yet widely covered by insurance, so results may not apply broadly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

Oct 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The University of Chicago has a prospectively maintained database (LYMPHA Database) of all patients who were candidates for ILR.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All patients who were candidates for Immediate Lymphatic Reconstruction (ILR) Exclusion Criteria: * None

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Conditions

The condition(s) this trial relates to.

lymphedema prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lymphatic reconstruction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The University o Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

More trials for these conditions

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