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New surgery aims to stop arm swelling in breast cancer survivors

NCT ID NCT03990610

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 33 times

Summary

This study tests whether moving lymph nodes from one part of the body to the armpit during breast reconstruction can lower the risk of lymphedema, a painful arm swelling. Thirty breast cancer patients who had mastectomy and lymph node removal will receive the extra procedure. Researchers will track how many develop lymphedema over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vascularized lymph node transfer (surgical procedure)

What this could lead to

If it works, this could offer a way to prevent chronic arm swelling after breast cancer treatment, improving quality of life.

What could go wrong

This is a small, early-stage study with only 30 participants and no control group, so results may not be conclusive. Surgery carries risks like infection or poor healing.

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.