New gel shows promise for speeding up wound healing in early trial
NCT ID NCT07463378
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests a gel called LUT017 on small skin wounds from mole removals in healthy adults. Each person gets the gel on one wound and a placebo on another to compare healing. The goal is to see if the gel is safe and might help wounds close faster. Only 9 people will take part, and they are followed for about one week.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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About 9 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria 1. Subjects scheduled to undergo excision of two or more clinically benign skin lesions (e.g., melanocytic nevi or seborrheic keratoses) that will result in at least two comparable acute cutaneous wounds suitable for study treatment. 2. Subject must be ≥ 18 years of age. 3. Subjects must be in generally good health, with no dermatologic or systemic condition that may impair normal wound healing, as determined by the Investigator. 4. Lesions selected for excision must be benign, confirmed clinically by the treating dermatologist or surgeon prior to the procedure. 5. Must be able and willing to provide informed consent prior to study participation. 6. Female subjects of childbearing potential must have a negative pregnancy test at day 0. They should agree to use highly effective methods of birth control, defined as those with failure less than 1%, such as implants, injectables, combined oral contraceptives, some intrauterine contraceptive devices (IUD's), sexual abstinence, or a vasectomized partner. Exclusion Criteria 1. Any lesion scheduled for excision that is suspicious for malignancy or has not been clinically assessed as benign by the treating dermatologist or surgeon. 2. History of abnormal wound healing, including keloid formation, hypertrophic scarring, chronic non-healing wounds, or delayed healing after prior procedures. 3. Target ulcer shows any signs of infection (only non-infected ulcers are eligible). 4. Unable to tolerate multi-layer bandages or compression garments. 5. Decompensated congestive heart failure. 6. Active soft tissue or bone infection requiring antibiotics. 7. Skin cancer on the target limb within the last 24 months. 8. Actively receiving chemotherapy and/or radiation therapy for cancer. 9. Treatment with a serine/threonine-protein kinase BRAF inhibitor, including but not limited to Zelboraf® (vemurafenib), Tafinlar® (dabrafenib), BraftoviTM (encorafenib) or Nexavar® (sorafenib), within 30 days or 5 half-lives of the drug prior to Day 0, whichever is longer. 10. Blood chemistry and complete blood count (CBC) values from the most recent laboratory assessment performed within the past 12 monsth: 1. White Blood Cells (WBC) \< 1.5 x 109/L. 2. Absolute \< 0.9 x 109/L. 3. Platelet count \< 50 x 109/L. 4. Alanine aminotransferase \> 3 x upper limit of normal. 5. Aspartate aminotransferase \> 3 x upper limit of normal. 6. Serum albumin \<2.0 g/dL. 11. Current use of systemic corticosteroids \> 5 mg daily or equivalent within 4 weeks. 12. Currently pregnant or trying to become pregnant. 13. Inability or unwillingness to participate in all aspects of study protocol or as determined by the Investigator. 14. Known hypersensitivity to the ingredients of the study drug. 15. No known history of diabetis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of California, Los Angeles
Los Angeles, California, 90095, United States
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