Ultrasound-Guided breathing support tested for chest injuries
NCT ID NCT06072339
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether using lung ultrasound to adjust ventilator pressure could improve oxygen levels in people with blunt chest trauma. Nineteen adults with rib fractures or lung bruises who needed breathing support were enrolled. The trial was terminated early, so the findings are limited.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- lung ultrasound guidance for ventilator settings
- What this could lead to
- If successful, this approach could help doctors set ventilator pressure more precisely for chest trauma patients, potentially improving oxygen levels.
- What could go wrong
- The trial was terminated early with only 19 participants, so results are very limited. The technique may not work better than standard care and requires skilled ultrasound operators.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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19 people
The number who actually took part.
- Started
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Dec 2023
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 or more * Admitted to intensive care or continuing care for 72 hours or less for blunt chest trauma, defined by the presence of at least one of the following elements on the initial CT scan: fracture(s) of rib(s) / fracture(s) of the sternum / pulmonary contusion / hemothorax * Acute hypoxemic respiratory failure defined by the administration of oxygen at least 3 L/min with nasal cannula or FiO2≥30% if high flow oxygen therapy. * Patient with a functional arterial catheter for blood tests Exclusion Criteria: * Acute respiratory distress, defined by the presence of at least one of the following clinical signs: respiratory rate ˃ 35 / use of accessory inspirators / paradoxal abdominal or thoracic motion * Imminent need for invasive mechanical ventilation * Usual contraindication to non-invasive ventilation (undrained pneumothorax, trauma to the face, vigilance disorders, digestive bleeding, hemodynamic instability, intolerance) * Hypercapnia (PaCO2˃45mmHg) * Patient unable to cooperate, communicate * Therapeutic limitation * Expected length of stay ≤ 48h * Severe head trauma * Pregnant or breastfeeding women * Participation in other clinical research related to respiratory failure/respiratory therapy * Vulnerable people * Protected adults, under guardianship or curatorship, or unable to give consent * Non-affiliated person or beneficiary of a social security scheme * Absence of free, informed and written consent, signed by the participant and the investigator
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UH of Montpellier
Montpellier, Montpellier, 34295, France
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