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Which lung re-inflation method is safer after surgery?

NCT ID NCT07247500

Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at two different methods doctors use to re-inflate a lung after it has been collapsed during surgery. About 350 people having lung surgery will take part. The goal is to see which method leads to fewer lung problems like pneumonia or collapsed air sacs in the week after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 350 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ASA score ≤ 3. * Undergoing a scheduled video-assisted or robot-assisted lobectomy or segmentectomy. * Patient has read and understood the information sheet and signed the informed consent form. * For women of childbearing potential, effective contraception and confirmation of the absence of an ongoing pregnancy by a negative blood or urine pregnancy test are required. * Postmenopausal women (spontaneous, non-medically induced amenorrhea for at least 12 months prior to the inclusion visit). * Patient affiliated with a social security system. Exclusion Criteria: * Patients with a BMI \> 40 kg/m². * Patients with severe chronic respiratory failure (COPD grade 3, FEV₁/FVC \< 0.7 and FEV₁ \< 50% - according to the GOLD 2025 classification). * Patients with severe chronic renal failure (GFR \< 30 mL/min). * Patients at high risk of conversion to thoracotomy. * Patients with a history of acute respiratory distress syndrome (ARDS) within 3 months prior to surgery. * Patients with a known history of severe hepatic failure (Child-Pugh class B or C). * Patients with a history of heart failure (NYHA class ≥ II). * Patients with a history of pulmonary resection. * Patients with uncontrolled asthma. * Pregnant or breastfeeding women. * Patients deprived of liberty by administrative or judicial decision, as well as those under legal protection, guardianship, or curatorship.

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Conditions

The condition(s) this trial relates to.

lung cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung surgery

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU d'AMIENS

    Amiens, 80054, France

  • CHU de LILLE

    Lille, 59037, France

  • CHU de ROUEN

    Rouen, 76031, France

  • Clinique Victor Pauchet

    Amiens, 80094, France

  • Hopital Foch

    Suresnes, 92150, France

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