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Simple breathing exercises cut lung problems after brain surgery by more than half

NCT ID NCT07571759

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

After brain tumor surgery, some patients develop lung issues like pneumonia. This study tested a new nursing system that includes breathing exercises, early movement, and team care. In 165 patients, the new system reduced lung complications from 13.6% to 4.8% and helped patients recover faster.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
perioperative pulmonary rehabilitation nursing system (PPRNS)
What this could lead to
If it works, this could become a standard nursing protocol to prevent lung complications and speed up recovery after brain tumor surgery.
What could go wrong
This is a small, single-center study. Results may not apply to all hospitals or patients. The nursing system requires extra training and resources.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

165 people

The number who actually took part.

Started

Feb 2025

Finished

Dec 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 75 years, inclusive Preoperative diagnosis of intracranial tumor confirmed by imaging and/or pathology per WHO Classification of Tumours of the Central Nervous System (5th edition), with planned craniotomy for tumor resection (initial or recurrent surgery) Preoperative assessment confirms ability to cooperate with pulmonary rehabilitation training (adequate consciousness, cognition, and communication for short-term training) Voluntary participation with written informed consent Exclusion Criteria: * Pre-existing severe chronic obstructive pulmonary disease (COPD GOLD stages 3-4) Pre-existing severe interstitial lung disease Requirement for long-term oxygen therapy Pneumonia or respiratory failure requiring mechanical ventilation within one month prior to surgery Severe cardiac dysfunction (New York Heart Association class III-IV) Other major organ insufficiency Severe impairment of consciousness Inability to follow commands Language barriers Life expectancy less than 30 days Concurrent participation in other interventional studies that could confound pulmonary function outcomes

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Affiliated Brain Hospital of Nanjing Medical University

    Nanjing, Jiangsu, 210029, China