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AI-Powered chest X-Rays could revolutionize lung cancer screening in latin america

NCT ID NCT07524803

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will enroll 2,000 people aged 50 or older in Mexico, Costa Rica, Colombia, and Argentina who are at high risk for lung cancer due to smoking, wood smoke exposure, family history, or COPD. Participants will get a chest X-ray analyzed by artificial intelligence and a low-dose CT scan to see if the AI can help decide who needs follow-up scans. The goal is to improve early detection of lung nodules in a region where screening guidelines are still being developed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Low-dose CT scan and chest X-ray with AI analysis
What this could lead to
If successful, this could show that combining AI with chest X-rays helps identify who needs a CT scan, making lung cancer screening more accessible in Latin America.
What could go wrong
This is an observational study, not a treatment trial. It may not prove that screening saves lives, and results may not apply to other regions or risk groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,000 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

May 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

2000 patients will be recruited in 4 Latin American countries (Mexico 700 pts,Costa Rica 300 pts, Colombia 500 pts, Argentina 500 pts)

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1\. Men and women ≥50 years of age and one of any of the following criteria: 1. Exposure to wood smoke (at least 100 hours per year) 2. A family history of lung cancer in first-degree relatives 3. A diagnosis of COPD and/or emphysema 4. Smokers with a tobacco index of 10 years or more Exclusion Criteria: 1. Lung cancer diagnosis or any other type of active cancer during the 5 years prior to the screening 2. Incomplete clinical information 3. Loss of 10% of the baseline weight during 6 months prior to study entry 4. Having a functional status, psychiatric condition or comorbidity that precludes curative treatment 5. Any situation that makes the subject ineligible for LDCT 6. Life expectancy ≤5 years 7. Subjects with previous history of pulmonary nodules.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CTIC

    Bogotá, Colombia

  • Centro de Investigacion y Manejo del Cancer (CIMCA)

    San José, Provincia de San José, 10103, Costa Rica

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