AI-Powered chest X-Rays could revolutionize lung cancer screening in latin america
NCT ID NCT07524803
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will enroll 2,000 people aged 50 or older in Mexico, Costa Rica, Colombia, and Argentina who are at high risk for lung cancer due to smoking, wood smoke exposure, family history, or COPD. Participants will get a chest X-ray analyzed by artificial intelligence and a low-dose CT scan to see if the AI can help decide who needs follow-up scans. The goal is to improve early detection of lung nodules in a region where screening guidelines are still being developed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Low-dose CT scan and chest X-ray with AI analysis
- What this could lead to
- If successful, this could show that combining AI with chest X-rays helps identify who needs a CT scan, making lung cancer screening more accessible in Latin America.
- What could go wrong
- This is an observational study, not a treatment trial. It may not prove that screening saves lives, and results may not apply to other regions or risk groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 2,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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May 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
2000 patients will be recruited in 4 Latin American countries (Mexico 700 pts,Costa Rica 300 pts, Colombia 500 pts, Argentina 500 pts)
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1\. Men and women ≥50 years of age and one of any of the following criteria: 1. Exposure to wood smoke (at least 100 hours per year) 2. A family history of lung cancer in first-degree relatives 3. A diagnosis of COPD and/or emphysema 4. Smokers with a tobacco index of 10 years or more Exclusion Criteria: 1. Lung cancer diagnosis or any other type of active cancer during the 5 years prior to the screening 2. Incomplete clinical information 3. Loss of 10% of the baseline weight during 6 months prior to study entry 4. Having a functional status, psychiatric condition or comorbidity that precludes curative treatment 5. Any situation that makes the subject ineligible for LDCT 6. Life expectancy ≤5 years 7. Subjects with previous history of pulmonary nodules.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites in 2 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CTIC
Bogotá, Colombia
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Centro de Investigacion y Manejo del Cancer (CIMCA)
San José, Provincia de San José, 10103, Costa Rica
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